Fluconazole

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DRUG:

Fluconazole is an antifungal medication used to prevent and treat a variety of fungal and yeast infections.

USE:

Take this medication by mouth, with or without food, usually once a day, or as directed by your doctor. This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, remember to use it at the same time each day as directed. Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days to decrease likelihood of reinfection. Inform your doctor if you condition persists or worsens.

CAUTIONS:

Before taking fluconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungal drugs (e.g. ketoconazole, itraconazole). Before using this medication, tell your doctor or pharmacist your medical history, especially of heart disease, liver disease or kidney disease. Although uncommon, this drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication should be used only when clearly needed during pregnancy. Fluconazole passes into breast milk; consult your doctor.

POSSIBLE SIDE EFFECTS:

Nausea, vomiting, diarrhea, stomach upset/pain, headache, dizziness, or hair loss may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects, and many people using this medication do not have serious side effects. This drug may rarely cause serious (possibly fatal) liver disease. If you notice any of these highly unlikely but serious side effects, seek immediate medical attention: severe stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes or skin, dark urine, unusual tiredness. A serious allergic reaction to this drug is unlikely but seek immediate medical attention if one occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness and trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

DRUG INTERACTIONS:

This drug should not be used with the following medications because very serious interactions may occur: astemizole, cisapride, terfenadine. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: amitriptyline, certain anti-diabetic drugs (sulfonylureas such as glipizide, glyburide, tolbutamide), certain benzodiazepines (e.g. alprazolam, midazolam, triazolam), “blood thinners” (e.g. warfarin), certain calcium channel blockers (e.g. felodipine, nifedipine) carbamazepine, certain COX-2 inhibitors (e.g. celecoxib, valdecoxib), certain drugs that affect the immune system (e.g. cyclosporine, tacrolimus), eplerenone, phenytoin, refamycins (e.g. rifabutin, rifampin), and theophylline. Do not start or stop any medicine without doctor approval. This medicine can decrease the effectiveness of oral contraceptives. To prevent pregnancy, use an additional form of birth control while taking this medication.

OVERDOSE:

If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Symptoms of overdose may include hallucinations and mental/mood changes.